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Homozygous GNAS 393C-Allele Carriers with Locally Advanced Esophageal Cancer Fail to Benefit from Platinum-Based Preoper...

Alakus, Hakan Bollschweiler, Elfriede Hölscher, Arnulf H. Warnecke-Eberz, Ute Frazer, Kelly A. Harismendy, Olivier Lowy, Andrew M. Mönig, Stefan P. Eberz, Pascal M. Maus, Martin ...

Published in Annals of Surgical Oncology

BackgroundCurrently, patients with locally advanced esophageal cancer receive neoadjuvant chemoradiotherapy but only about half of these patients benefit from this treatment. GNAS T393C has been shown to predict the postoperative course in solid tumors and may therefore be useful for treatment stratification. The aim of the present study was to det...

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